Simultaneous Multi-Laser Nanoparticle Tracking Analysis (NTA)

            The HORIBA ViewSizer™ 3000 is a next-generation nanoparticle tracking analyzer that revolutionizes the way polydisperse samples are measured. Unlike conventional NTA systems, it integrates three simultaneous lasers with independently adjustable power, enabling accurate detection of particles from 10 nm to 15 µm across highly heterogeneous samples. With advanced optics, intuitive software, and a vertical sample introduction design, the ViewSizer™ 3000 provides unmatched visualization and quantification of nanoparticles, including size, subpopulations, concentration, fluorescence, and sedimentation.

• Triple-Laser Technology – Simultaneous use of blue, green, and red lasers ensures accurate detection across a broad size range, eliminating bias from larger particles.
• Comprehensive Multi-Parameter Analysis – Measures size distribution, concentration, fluorescence, and sedimentation behavior in a single system.
• Unmatched Sample Versatility – Handles polydisperse, fluorescent, and non-aqueous solvent-based samples with precision.
• User-Friendly Operation – Simple workflow: load sample, record, and analyze with intuitive software and real-time visualization.
• Vertical Sample Introduction – Reduces cross-contamination, allows mixing during measurements, and enables broader particle size analysis via sedimentation.
• Applications Across Industries – Ideal for extracellular vesicles (EVs), viruses, proteins, lipid nanoparticles (LNPs), microplastics, polymers, colloids, water treatment, graphene, and battery research.
• High Accuracy & Reproducibility – Advanced optical design, precise scattering volume determination, and controlled temperature system (10 °C to 50 °C).

How it Works – ViewSizer™ 3000
The ViewSizer™ 3000 characterizes nanoparticles by analyzing their Brownian motion and micron-sized particles through gravitational settling. Using advanced light scattering, high-resolution video cameras, and powerful image processing, each particle’s movement is tracked to determine diffusion coefficients and particle size distribution. This allows accurate visualization and quantification of highly polydisperse samples.

       

With its unique vertical quartz cuvette design (with insert, stir bar, and cap), the system delivers significant advantages:

Sample Mixing During Recording – Ensures more representative, repeatable, and reproducible results.
Non-Aqueous Compatibility – Accurately handles particles dispersed in solvents such as xylene or alcohols.
Safe Sample Handling – Enclosed cuvette design enables safer transfer and analysis of hazardous materials.